1 Department of Social Work, Rabindra Bharati University Centre for Distance and Online Education, EE 9 & 10 Sector II, Salt Lake City (Near Karunamayee), Kolkata, West Bengal, India.
2 Department of Pharmaceutics, School of Pharmacy, Sister Nivedita University, DG 1/2 New Town, Action Area 1, Kolkata, West Bengal, India.
Research Article
World Journal of Advanced Research and Reviews, 2024, 24(01), 978-982
Article DOI: 10.30574/wjarr.2024.24.1.3122
Received on 02 September 2024; revised on 08 October 2024; accepted on 11 October 2024
As per the observation of the social work activitist it was found that the raw extract of the root of Sida cordifolia Linn. Are been used by some old people in the village of Falta Block of South 24 PGS district of West Bengal, India to treat epileptic attack on some villagers. The identified plant were collected and handed over the research scientists for the further study. The dried coarse powder of the root of Sida cordifolia Linn. Were soxheleted successively with petroleum ether (PESC), methanol (MESE), with boiled water (AESC) and the epileptic study was performed on the Albino mice using 100 and 300 mg/kg body weight of PESC, MESE and using clonazepam as standard using Maximum Electroshock induced seizure model and result depicted that PESC exhibited a significant antiepileptic effect at both low and high doses where as MESC exhibited the significant antiepileptic effect only at high dose. Hence, the petroleum ether extract may be chosen to be more effective than that of the methanol extract.
Sida cordifolia Linn; Soxheleted, Methanol; Antiepileptic; Clonazepam; Petroleum ether extract
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Munmun Mondal and Partha Niyogi. Sida cordifolia Linn- An widely used herbs in the village of Falta, west Bengal, India: Pharmacological evaluation of antiepileptic activity of root extract of Sida cordifolia Linn.. World Journal of Advanced Research and Reviews, 2024, 24(1), 978-982. Article DOI: https://doi.org/10.30574/wjarr.2024.24.1.3122