Serum Vitamin D concentrations and their association with the clinical severity of vitiligo
1 General Physician, Universidad Autónoma de Bucaramanga, Colombia.
2 General Physician, Universidad Del Sinú, Cartagena, Colombia.
3 General Physician, Universidad Del Norte, Barranquilla, Colombia.
4 General Physician, Universidad Privada Antenor Orrego, Perú.
5 General Physician, Universidad de Boyacá, Colombia.
6 General Physician, Universidad de Sucre, Colombia.
7 General Physician, Universidad del Sinú, Colombia.
8 Intern Physician, Universidad Autónoma de Bucaramanga, Colombia.
Review Article
World Journal of Advanced Research and Reviews, 2022, 14(01), 001–006
Article DOI: 10.30574/wjarr.2022.14.1.0218
Publication history:
Received on 04 February 2022; revised on 26 March 2022; accepted on 28 March 2022
Abstract:
Vitiligo is the most common acquired depigmentation of the skin, affecting the patient's self- image and negatively affecting quality of life. As for the pathogenesis of vitiligo, there is an autoimmune theory. Vitamin D deficiency has been shown to exist in many autoimmune diseases. Vitamin D is an essential hormone with pleiotropic effects, especially anti-apoptosis and regulatory functions of melanocyte proliferation and differentiation. It has been hypothesized that it may play a supportive role in the repigmentation of white matter lesions. The immunomodulatory activity of vitamin D may be used to treat vitiligo.
Keywords:
Vitiligo; Vitamin D; Vitamin D Concentrations; Severity
Full text article in PDF:
Copyright information:
Copyright © 2022 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0