A scoping review of mesenchymal stem cell metabolites: Implications for oral wound healing
1 Department of Oral Medicine, Faculty of Dental Medicine, Airlangga University, Surabaya, East Java, Indonesia.
2 Department of Oral Medicine, Airlangga University, Surabaya, East Java, Indonesia.
Review Article
World Journal of Advanced Research and Reviews, 2024, 24(03), 1839-1845
Publication history:
Received on 02 November 2024; revised on 11 December 2024; accepted on 13 December 2024
Abstract:
Mesenchymal stem cell (MSC) metabolites show considerable promise in enhancing oral wound healing due to their regenerative properties, including anti-inflammatory, collagen-promoting, and angiogenesis-stimulating effects. This scoping review consolidates current research on MSC metabolites, focusing on their roles in accelerating wound closure, reducing infection risk, and improving tissue integrity within the unique environment of the oral cavity. The findings reveal that while MSC metabolites offer a novel therapeutic approach with significant potential benefits, challenges such as variations in metabolite and quality need to be addressed to ensure consistent clinical outcomes. This review highlights the need for further studies to refine MSC metabolite applications, aiming to improve wound healing treatment efficacy in dentistry and oral health care.
Keywords:
Mesenchymal Stem Cells; MSC Metabolites; Oral Wound Healing; Regenerative Medicine; Tissue Repair; Anti-Inflammatory; Collagen Synthesis; Angiogenesis
Full text article in PDF:
Copyright information:
Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0