The role of maternal serum alpha-fetoprotein in preterm birth: A literature review
1 Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
2 Department of Pediatrics, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
3 Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Review Article
World Journal of Advanced Research and Reviews, 2023, 18(03), 738–741
Article DOI: 10.30574/wjarr.2023.18.3.1158
Publication history:
Received on 01 May 2023; revised on 13 June 2023; accepted on 15 June 2023
Abstract:
Preterm birth is one of the most important global issues. Mortality and morbidity among children under 5 years, including neonates, is affected by preterm birth. A good maternal care, health workers, and health facilities play an important role in the outcome of pregnancy, including preterm birth. An early screening test for pregnancy is crucial to find any abnormality thus preterm birth can be predicted and the following treatment may be applied without delay. One of potential biomarker for the screening test is alpha-fetoprotein (AFP) that can be found in maternal serum. Web-based literature search was carried out using several keywords. This literature review aims to collect data and articles to conclude the correlation of the potential biomarkers in diagnostic of preterm birth.
Keywords:
Preterm Birth; Alpha-Fetoprotein; Maternal Serum; Biomarker; Pregnancy
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0