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eISSN: 2582-8185 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in March 2026 (Volume 29, Issue 3) Submit manuscript

The review on versatile study of Alzheimer’s Disease (AD) and their etiology, pathophysiology, common mechanism of action of drugs used in current treatment

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  • The review on versatile study of Alzheimer’s Disease (AD) and their etiology, pathophysiology, common mechanism of action of drugs used in current treatment

J. Aruna *, A. Lokesh, G. Madhavan V. Dhanalakshmi, R. Guhan, S. Kaviya,  A.Sanjay, P. Saranyadevi and P. Surekha

Department of Pharmacology, KG College of Pharmacy and Research Institute-605 203.

Review Article

World Journal of Advanced Research and Reviews, 2026, 29(02), 631-644

Article DOI: 10.30574/wjarr.2026.29.2.0330

DOI url: https://doi.org/10.30574/wjarr.2026.29.2.0330

Received on 31 December 2025; revised on 09 February 2026; accepted on 11 February 2026

Alzheimer’s complaint (announcement) is the most common habitual neurodegenerative complaint worldwide and a leading cause of madness. It results in cognitive impairments similar as aphasia and agnosia, along with behavioral and cerebral symptoms that place a significant emotional and fiscal burden on cases and their families. First described by Alois Alzheimer in 1907, announcement is classified into domestic and sporadic forms. presently, over 47 million people are affected encyclopedically, with figures anticipated to rise sprucely by 2050. The complaint is characterized by amyloid pillars and neurofibrillary befuddlements formed by amyloid- β and tau proteins. Announcement is multifactorial, with the cholinergic and amyloid suppositions being central to its pathogenesis. This review summarizes recent advances in announcement mechanisms, memory impairment, opinion, treatment strategies, and ongoing clinical exploration.

Alzheimer’s; Dementia; Cognitive Impairment; Tau Protein; Amyloid Beta

https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2026-0330.pdf

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J. Aruna, A. Lokesh, G. Madhavan V. Dhanalakshmi, R. Guhan, S. Kaviya, A.Sanjay, P. Saranyadevi and P. Surekha. The review on versatile study of Alzheimer’s Disease (AD) and their etiology, pathophysiology, common mechanism of action of drugs used in current treatment. World Journal of Advanced Research and Reviews, 2026, 29(2), 631-644. Article DOI: https://doi.org/10.30574/wjarr.2026.29.2.0330

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