Department of Pharmacy, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Sri Lanka.
Review Article
World Journal of Advanced Research and Reviews, 2022, 15(03), 214-221
Article DOI: 10.30574/wjarr.2022.15.3.0916
Received on 10 August 2022; revised on 15 September 2022; accepted on 17 September 2022
Nanoemulgel is an emergent and promising drug delivery system used nowadays in the pharmaceutical industry. As a novel transdermal drug delivery tool, the applications of nanoemulgel have increasingly been used due to their unique characteristic properties and benefits over other oral and topical drug deliveries to avoid poor drug bioavailability and pharmacokinetic variations. These nanoemulgels are principally oil-in-water nanoemulsions gelled with a certain gelling agent in them. Plant extracts provide remarkable therapeutic options to manage different disease conditions due to their various pharmacological activities such as antioxidant, anti-inflammatory, anti-cancer, antibacterial, etc. However, the poor solubility and low bioavailability of lipophilic phytochemicals in plant extracts are two major issues in developing plant-derived formulations. In the past years, pharmaceutical research has focused more on nano-scale delivery systems to overcome the above problems by improving the delivery of herbal extracts and they have also reported nanoemulgel as a good vehicle for lipophilic and poorly soluble drugs. Therefore, the objective of this review is to discuss recent studies and applications of plant-derived nanoemulgels.
Nanoemulgel; Plants; Nanotechnology; Therapeutic application
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Warnakulasuriya Thanujee Fernando, Athuraliya Gamacharige Kasuni Neranja and Samamalee Upekshi Kankanamge. A review on various plant-derived nanoemulgels and their applications. World Journal of Advanced Research and Reviews, 2022, 15(3), 214-221. Article DOI: https://doi.org/10.30574/wjarr.2022.15.3.0916