A review on synthesis methods of tricyclic 1,2,3,4-tetrahydrocarbazoles
1 Sanskar College of Pharmacy and Research (SCPR), Opp. Jindal Pipes ltd, NH-24, Jindal Nagar, Ghaziabad, Uttar Pradesh 201302.
2 OM Sterling Global University, NH-52, Hisar-Chandigarh Road, Hisar, Haryana 125001.
Review Article
World Journal of Advanced Research and Reviews, 2022, 13(01), 160–171
Article DOI: 10.30574/wjarr.2022.13.1.0754
Publication history:
Received on 28 November 2021; revised on 04 January 2022; accepted on 06 January 2022
Abstract:
In this review article, we discussed old to new synthetic methods used for the preparation of 1,2,3,4-Tetrahydrocarbazole (THCz) based on reported literature. Around the worldwide, various researchers energetically reported new synthetic methods for tetrahydrocarbazoles preparation using conventional method or microwave method or use of catalyst. This review will be helpful to synthetic and medicinal chemist to find selective method for the preparation of 1,2,3,4-Tetrahydrocarbazoles with good percentage yield and less time. This review will also useful to medicinal chemist to design new biologically active tetrahydrocarbazoles based on reported synthetic methods.
Keywords:
Tetrahydrocarbazole (THcz); Synthesis; Fischer Indole; Microwave (MW)
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