A review on recent advances in antibiotic therapy for endoscopic ultrasound-guided pancreatic tumor biopsy
Resident in Endoscopy at the Digestive Endoscopy Department of Federal University of São Paulo (UNIFESP), São Paulo, Brazil.
Review Article
World Journal of Advanced Research and Reviews, 2024, 21(01), 1766–1770
Publication history:
Received on 10 December 2023; revised on 17 January 2024; accepted on 19 January 2024
Abstract:
Pancreatic tumors requiring biopsy present a clinical challenge necessitating precise interventions. Endoscopic ultrasound (EUS) has emerged as a crucial tool for guiding these biopsies, offering real-time imaging and enhanced procedural accuracy. However, infectious complications following EUS-guided procedures, particularly needle punctures, underscore the importance of judicious antibiotic therapy.
This review explores recent literature focusing on refining antibiotic strategies to minimize infection-related complications associated with EUS-guided pancreatic tumor biopsies. A comprehensive search across electronic databases identified 362 articles, with 32 meeting inclusion criteria for full-text assessment. The selected articles encompassed a variety of study designs, including retrospective and prospective studies, randomized controlled trials (RCTs), and reviews, reflecting the evolving nature of research in this field.
The primary objective of this review is to critically evaluate recent literature on the necessity of antibiotic therapy and prophylaxis following EUS-guided pancreatic tumor biopsy.
The discussion highlights the lack of consensus in establishing standardized antibiotic protocols for EUS-guided pancreatic tumor biopsy, with varying approaches from broad-spectrum prophylaxis to tailored therapeutic interventions. Factors such as needle type, number of passes, and the presence of cystic lesions contribute to distinct infectious risk profiles, necessitating a nuanced approach to antibiotic selection and duration.
Keywords:
Pancreatic tumors; Endoscopic ultrasound (EUS); Antibiotic therapy; Fine-needle aspiration (FNA); Fine-needle biopsy (FNB)
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Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0