Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra-136119, India.
Review Article
World Journal of Advanced Research and Reviews, 2021, 09(01), 086-096
Article DOI: 10.30574/wjarr.2021.9.1.0472
Received on 10 December 2020; revised on 22 December 2020; accepted on 25 December 2020
1, 3, 4-oxadiazole derivatives received considerable attention of different research groups, as they have wide variety of biological activities. 1, 3, 4-oxadiazole derivatives exhibited noteworthy anticancer activities. In recent years, microwave-induced organic reactions attained significant attention due to several benefits, such as short reaction time, cost-effectiveness, excellent yield, and ease of work. In view of above in present work, SAR and mechanism of action of 1, 3, 4-oxadiazole derivatives as anticancer agents, reported by different research groups in recent years are summarized. Present review also highlighted the various synthetic approaches for efficient microwave-assisted green synthesis of 1, 3, 4-oxadiazole derivatives.
1, 3, 4-Oxadiazole derivatives; Structure activity relationship (SAR); Mechanism of action (MOA); Anti-cancer, Microwave-assisted green synthesis
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Deeksha Tiwari, Rakesh Narang and Sukhbir Lal khokra. A review on microwave assisted synthesis, mechanism of action and structure activity relationship of 1, 3, 4-oxadiazole derivatives as anticancer agent. World Journal of Advanced Research and Reviews, 2021, 9(1), 086-096. Article DOI: https://doi.org/10.30574/wjarr.2021.9.1.0472