A review on microwave assisted synthesis, mechanism of action and structure activity relationship of 1, 3, 4-oxadiazole derivatives as anticancer agent
Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra-136119, India.
Review Article
World Journal of Advanced Research and Reviews, 2021, 09(01), 086-096
Article DOI: 10.30574/wjarr.2021.9.1.0472
Publication history:
Received on 10 December 2020; revised on 22 December 2020; accepted on 25 December 2020
Abstract:
1, 3, 4-oxadiazole derivatives received considerable attention of different research groups, as they have wide variety of biological activities. 1, 3, 4-oxadiazole derivatives exhibited noteworthy anticancer activities. In recent years, microwave-induced organic reactions attained significant attention due to several benefits, such as short reaction time, cost-effectiveness, excellent yield, and ease of work. In view of above in present work, SAR and mechanism of action of 1, 3, 4-oxadiazole derivatives as anticancer agents, reported by different research groups in recent years are summarized. Present review also highlighted the various synthetic approaches for efficient microwave-assisted green synthesis of 1, 3, 4-oxadiazole derivatives.
Keywords:
1, 3, 4-Oxadiazole derivatives; Structure activity relationship (SAR); Mechanism of action (MOA); Anti-cancer, Microwave-assisted green synthesis
Full text article in PDF:
Copyright information:
Copyright © 2021 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0