Review on brain-targeted drug delivery

Dilip Kumar Uikey * and Shubham Maroti Shende

Department of Pharmaceutics, School of pharmacy, G H Raisoni University, Saikheda, MP, India.
 
Review Article
World Journal of Advanced Research and Reviews, 2023, 18(03), 1489–1494
Article DOI: 10.30574/wjarr.2023.18.3.1265
 
Publication history: 
Received on 20 May 2023; revised on 27 JUne 2023; accepted on 30 June 2023
 
Abstract: 
Brain-targeted drug delivery is a field of research that seeks to develop new methods for delivering drugs to the brain. This is done by overcoming the blood-brain barrier (BBB), a network of cells that tightly regulate the flow of substances between the blood and the brain. Most of the time lipophilic drugs are easily cross blood brain barrier but few of them less soluble in lipid therefore they don’t cross the blood brain barrier. After review we concluded that we can easily improve the solubility of drug using various techniques and Brain-targeted drug delivery is a promising field of research that has the potential to revolutionize the treatment of brain diseases. With further advances, it is possible that brain-targeted drug delivery will become a standard treatment for a variety of brain diseases and disorders.
 
Keywords: 
Blood Brain Barrier; Brain-Targeted; CNS; Lipophilic drug; Challenges
 
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