The relationship of complete blood count on the outcome of childhood patients with Dengue Shock Syndrome (DSS) in the Pediatric Intensive Care Unit (PICU) Dr. Soetomo General Hospital

Muhammad Busral Hana 1, Neurinda Permata Kusumastuti 1, 2, *, Paulus Budiono Notopuro 1, 3 and Dominicus Husada 1, 2

1 Faculty of Medicine, Universitas Airlangga, Jl. Prof. Mayjen Dr. Moestopo ,47, Surabaya East Java, 60131, Indonesia.
2 Department of Pediatrics, Universitas Airlangga/ Soetomo General Hospital Surabaya, Indonesia.
3 Department of Clinical Pathology, Universitas Airlangga/ Soetomo General Hospital Surabaya, Indonesia.
 
Research Article
World Journal of Advanced Research and Reviews, 2023, 20(03), 1738–1742
Article DOI: 10.30574/wjarr.2023.20.3.2659
 
Publication history: 
Received on 19 November 2023; revised on 27 December 2023; accepted on 29 December 2023
 
Abstract: 
Dengue Hemorrhagic Fever (DHF) is an acute infectious disease caused by the dengue virus which is spread through the bite of female mosquitoes of the Aedes Aegypti and Aedes Albopictus species. DHF cases often attack children under 15 years of age and if not treated properly it will turn into Dengue Shock Syndrome (DSS). Supporting examinations are needed to diagnose and monitor the condition of DSS patients, one of which is a complete blood test. This study aims to determine the relationship between a complete blood profile and the parameters: platelet count, leukocyte count, hematocrit value, and hemoglobin level on the outcome of pediatric patients with DSS in the Pediatric Intensive Care Unit (PICU) at the Regional General Hospital (RSUD) Dr. Soetomo. This research is a descriptive analytical observational study with a cross sectional approach using medical record data from pediatric patients with DSS in the PICU of Dr. RSUD. Soetomo Surabaya for the 2015-2022 period. The sample consisted of 40 samples in accordance with the inclusion and exclusion criteria taken using total sampling technique. In this study, a significant relationship was found between age, hemoglobin and leukocytes and the mortality outcome of pediatric DSS patients. The values obtained were <0.05 (age), 0.048 (hemoglobin), and 0.048 (leukocytes). Apart from that, there is also a significant relationship between platelets and the outcome of treatment duration for pediatric DSS patients.
 
Keywords: 
DSS; Complete Blood Count; Mortality; Length of Stay; Shock Duration
 
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