Recently investigated polymeric natural gums and mucilages for various drug delivery system
1Shambhunath Institute of Pharmacy, Jhalwa, Prayagraj, Uttar Pradesh-211012, India.
2 ARK College of Pharmacy, Sarai Akkil, Kaushambi, Uttar Pradesh-212216, India.
3Department of Pharmacy, Ashoka Institute of Technology and Management, Varanasi, Uttar Pradesh-221007, India.
Review Article
World Journal of Advanced Research and Reviews, 2020, 06(01), 050-072
Article DOI: 10.30574/wjarr.2020.6.1.0084
Publication history:
Received on 30 March 2020; revised on 06 April 2020; accepted on 07April 2020
Abstract:
The use of natural excipients to deliver the bioactive agents has been hampered by the synthetic materials. However advantages offered by these natural excipients are their being non-toxic, less expensive and freely available. The performance of the excipients partly determines the quality of the medicines. The traditional concept of the excipients as any component other than the active substance has undergone a substantial evolution from an inert and cheap vehicle to an essential constituent of the formulation. Gums are widely used natural excipients for conventional and novel dosage forms. With the increasing interest in polymers of natural origin, the pharmaceutical world has compliance to use most of them in the formulations. Since plant polysaccharides comply with many requirements expected of pharmaceutical excipients such as non-toxicity, stability, availability and renewability they are extensively investigated for use in the development of solid oral dosage forms. Furthermore, polysaccharides with varying physicochemical properties can be extracted from plants at relatively low cost and can be chemically modified to suit specific needs. Excipients are any component other than the active substance(s) intentionally added to formulation of a dosage form. This article gives an overview of herbal excipients which are used in conventional dosage forms as well as novel drug delivery systems.
Keywords:
Natural gum; Pharmaceutical excipient; NDDS; Polysaccharide
Full text article in PDF:
Copyright information:
Copyright © 2020 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0