A rare occurrence of Hodgkin lymphoma in a Xeroderma pigmentosum patient: A case report and literature review
1 Dermatology Department, Ibn rochd University hospital, Casablanca, Morocco.
2 Anatomical Pathology Department, Ibn rochd University hospital, Casablanca, Morocco.
Case Study
World Journal of Advanced Research and Reviews, 2024, 22(01), 1484–1486
Publication history:
Received on 07 March 2024; revised on 17 April 2024; accepted on 20 April 2024
Abstract:
Xeroderma pigmentosum (XP) is a rare genetic disorder characterized by extreme sensitivity to ultraviolet (UV) radiation, resulting in an increased risk of skin cancer and other UV-induced malignancies. Reports of hematological malignancies occurring in patients with XP are found in the literature, but they seem to be quite rare. This report describes a 29-year-old male patient with XP who developed Hodgkin lymphoma. The potential increased risk of lymphoma in XP patients is highlighted in this paper; however, further studies are needed to better understand the underlying mechanisms of lymphomagenesis in XP patients and to develop optimal treatment strategies for hematological and other internal malignancies in this setting.
Keywords:
Xeroderma pigmentosum; NER; Internal malignancies; Hodgkin lymphoma
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