A rare association between Xeroderma pigmentosum and diffuse large B-cell lymphoma: A case report
Department of Hematology, Mohammed VI hospital, Marrakech, Morocco.
Case Study
World Journal of Advanced Research and Reviews, 2023, 18(03), 031–034
Publication history:
Received on 22 April 2023; revised on 29 May 2023; accepted on 01 June 2023
Abstract:
Xeroderma pigmentosum (XP) is a rare genetic disorder characterized by extreme sensitivity to ultraviolet (UV) radiation, resulting in an increased risk of skin cancer and other UV-induced malignancies. Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's lymphoma (NHL). It belongs to a group of cancers that affect the lymphatic system. Reports of DLBCL occurring in patients with XP are found in the literature but it seems to be quite rare.
This report described a 31-year-old female patient with XP who developed DLBCL. The potential increased risk of lymphoma in XP patients is highlighted in this paper however further studies are needed to better understand the underlying mechanisms of lymphomagenesis in XP patients and to develop optimal treatment strategies for DLBCL in this setting.
Keywords:
Lymphoma; Diffuse lymphoma large B-cell; Xeroderma pigmentosum; DLBCL; Case report
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