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eISSN: 2582-8185 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in March 2026 (Volume 29, Issue 3) Submit manuscript

Quality of sleep, fatigue and adherence to antiepileptic medications among patients with epilepsy

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  • Quality of sleep, fatigue and adherence to antiepileptic medications among patients with epilepsy

Jothipriya 1, *, Jasmin Anand 1, Alice Suresh 2, Vivek Mathew 3 and Mahasampath Gowri 3

1 College of Nursing, CMC, Vellore, Tamil Nadu, India.    
2 Department of Neuromedicine, CMC, Vellore, Tamil Nadu, India.
3 Department of Biostatistics, CMC, Vellore, Tamil Nadu, India.
 
Research Article
World Journal of Advanced Research and Reviews, 2023, 18(02), 814–824
Article DOI: 10.30574/wjarr.2023.18.2.0857
DOI url: https://doi.org/10.30574/wjarr.2023.18.2.0857
 
Received on 01 April 2023; revised on 15 May 2023; accepted on 17 May 2023
 
Epilepsy is the second most common neurological disorder which affects 70 million individuals worldwide. The study assesses the quality of sleep, fatigue and adherence to antiepileptic medications among patients with epilepsy (PWE). A quantitative descriptive correlation study design was adopted. The investigator used simple random sampling technique to select 100 patients with epilepsy, who fulfilled the inclusion criteria. Quality of sleep was assessed using “Pittsburgh Sleep Quality Index”, fatigue with “Modified Fatigue Impact Scale” and adherence of antiepileptic medications with “Adherence in Chronic Disease Scale” by Self reporting technique. The study revealed that the quality of sleep was poor in 64% of the subjects, while the remaining, 36% had good quality of sleep. Majorities (83%) of the epileptic patients were found to have no fatigue, 12% had mild fatigue and the remaining 5% had moderate fatigue. Majority (81%) of the subjects were adherent to antiepileptic medications, 18% were moderately adherent and only 1% of them were non-adherent. The study depicts a negative correlation r= -0.099 (p= 0.338) between fatigue and adherence to antiepileptic medications which is not significant (p> 0.01) and shows no correlation (r =0 .0295) (p = 0.771) between the quality of sleep and adherence to antiepileptic medications. The study highlights a positive correlation (r= 0.2831(p= 0.004) between fatigue and the quality of sleep, which is significant (p < 09820.01). The study concludes that attention related to sleep in patients with epilepsy has important implication for diagnosis, seizure control and a better quality of life.
 
Quality of sleep; Fatigue; Adherence; Antiepileptic Medications; Epilepsy
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2023-0857.pdf

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Jothipriya, Jasmin Anand, Alice Suresh, Vivek Mathew and Mahasampath Gowri. Quality of sleep, fatigue and adherence to antiepileptic medications among patients with epilepsy. World Journal of Advanced Research and Reviews, 2023, 18(2), 814-824 . Article DOI: https://doi.org/10.30574/wjarr.2023.18.2.0857

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