Department of Hematology, Avicenna Military Hospital, University hospital Mohammed VI, Faculty of medicine and pharmacy of Marrakech, Cadi Ayyad University, Marrakech, Morocco.
Case Study
World Journal of Advanced Research and Reviews, 2022, 16(03), 198-204
Received on 20 October 2022; revised on 30 November 2022; accepted on 03 December 2022
Pure erythroid leukemia (PEL) is an extremely rare type of acute myeloid leukemia (AML), accounting for fewer than 1% of all AML cases. A 16-year-old girl, without any medical history, presented fever, severe fatigue and mucocutaneous bleeding. Her peripheral blood smears showed myeloid blasts with deep basophilic cytoplasm and circulating erythroblasts. Her bone marrow aspiration showed a very rich marrow with 93% erythroblastic hyperplasia with 30% excess of proerythroblasts, and 4% of myeloblasts. PEL appeared to be the definitive diagnosis after evaluating the immunophenotypic findings. Her general condition deteriorated during medical diagnosis, and she died soon after starting chemotherapy.
Pure erythroid leukemia; PEL; Acute myeloid leukemia; AML; De novo
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Imane Ouahidi, Hicham Yahyaoui, Zineb Nassiri, Mustapha Aitameur and Mohamed Chakour. Pure erythroid leukemia De Novo in 16-years-old girl: A case report and literature review. World Journal of Advanced Research and Reviews, 2022, 16(3), 198-204. Article DOI: https://doi.org/10.30574/wjarr.2022.16.3.1303