Pulmonary metastases revealing a mixed germ cell tumor with a predominant yolk sac tumor component: A case report

Loubna Ajdir *, Lamyaa Chakib, Mohamed Ijim, Oussama Fikri and Lamyae Amro

Department of Pulmonology, Faculty of Medicine and Pharmacy, Caddy Ayad Universit, Errazi Hospital, Mohammed VI University Hospital, Marrakech, Morocco.
 
Case Study
World Journal of Advanced Research and Reviews, 2024, 24(01), 1190–1197
Article DOI: 10.30574/wjarr.2024.24.1.3090
 
Publication history: 
Received on 29 August 2024; revised on 06 October 2024; accepted on 09 October 2024
 
Abstract: 
Yolk sac tumor of the testis is rare in adults. Its diagnosis is histological, reproducing an extra-embryonic structure (endodermal sinus tissue). It can be present alone or associated with another component, thus forming a mixed germ cell tumor. Treatment involves orchiectomy and chemotherapy in extratesticular stages. Lymph node dissection is indicated if residual masses persist. These tumors are characterized by a poor prognosis at an advanced metastatic stage. However, we report the clinical case of a 69-year-old man who presented with pulmonary metastases from a mixed germ cell tumor of the testis with a predominant Yolk Sac Tumor component, treated by orchiectomy, chemotherapy, and lymph node dissection.
 
Keywords: 
Cancer; Mixed germ cell tumor; Yolk Sac Tumor; Testis; Metastases
 
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