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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in March 2026 (Volume 29, Issue 3) Submit manuscript

Prostate Cancer Volumetric Arc Therapy (VMAT) Analysis

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  • Prostate Cancer Volumetric Arc Therapy (VMAT) Analysis

Aime M Gloi *

Genesiscare, Radiation Oncology, Modesto, California, USA.
 
Research Article
World Journal of Advanced Research and Reviews, 2023, 19(01), 1033-1044
Article DOI: 10.30574/wjarr.2023.19.1.1311
DOI url: https://doi.org/10.30574/wjarr.2023.19.1.1311
 
Received on 04 June 2023; revised on 11 July 2023; accepted on 13 July 2023
 
Aim: The purpose of this study was to derive radiobiological parameters from the dose volume histogram of patients that undergone prostate cancer radiotherapy via the VMAT technique.
Material and Methods: A total of twenty-two cases of prostate cancer of 70.2 and 81 Gy were selected for this study. Radiobiological parameters were evaluated by the Poisson equation for the tumor and LKB model for organs at risk.
Results: For prostate tumor, the average TCP was 96.28, 86.45, 68.57 for α/β of 1.2, 3.0, and 10, respectively. The average EUD was 37.98 Gy, 59.23 Gy, 21.19 Gy, 20.65 Gy, 16.32 Gy, and 21.87 Gy for bladder, rectum, right femoral head, left femoral head, small bowel, and large bowel respectively. The average NTCP was 7.6 % for the rectum and negligible for other organs at risk.
Conclusion: NTCP for critical organs and TCP for prostate cancer can be determined via dose volume histogram.
 
Equivalent uniform dose; Normal tissue complication probability; Prostate cancer; VMAT; Tumor control probability
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2023-1311.pdf

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Aime M Gloi. Prostate Cancer Volumetric Arc Therapy (VMAT) Analysis. World Journal of Advanced Research and Reviews, 2023, 19(1), 1033-1044. Article DOI: https://doi.org/10.30574/wjarr.2023.19.1.1311

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