Prospective cohort study of coronary vascular diseases leading to left bundle branch block and its relationship with the age after follow up of five years

Jibran Ikram 1, Khuram Khan 2, Aimen James 3, Eemaz Nathaniel 4, Ayesha Zahid 5, Muhammad Awais Khan 6, Furqan Ul Haq 7, Abdul Mueed Bangash 8, Salah Uddin 9, Moeen Ikram 10, Marium Asif 11, Qazi M Farooq Wahab 12 and Muhammad Awais 13

Department of Medicine, Rehman Medical Institute, Pakistan.
2 Combined Military Hospital Rawalpindi, Pakistan.
3 Royal Bournemouth Hospital NHS Foundation, Pakistan.
4 Research Officer, Rehman Medical Institute, Pakistan.
5 Department of Medicine, Rehman Medical Institute, Pakistan.
6 Department of Medcine, Combined Military Hospital Abottabad, Pakistan.
Department of Radiation oncology, Shifa International Hospital Islamabad, Pakistan.
8 Department of Medicine, Khyber Teaching Hospital Peshawar, Pakistan.
9 Department of medicine, Rehman Medical Institute Peshawar, Pakistan.
10 Department of medicine, Frontier Medical and Dental College, Abbottabad, Pakistan.
11 Department of medicine, Jinnah Hospital Lahore, Pakistan.
12 Department of Medicine, Khyber Teaching Hospital, Pakistan.
13 Department Of Medicine, Kabir Medical College, Peshawar, Pakistan.
 
Research Article
World Journal of Advanced Research and Reviews, 2024, 23(01), 1335–1343
Article DOI: 10.30574/wjarr.2024.23.1.1990
 
Publication history: 
Received on 23 May 2024; revised on 12 July 2024; accepted on 15 July 2024
 
Abstract: 
Background: Left bundle branch block (LBBB) may be due to conduction system degeneration or in the background of myocardial infarction. It can be due to aortic valve disease Myocardial disease may be reflected in the left bundle branch block, or it may be the result of conduction system degeneration. It may also develop due to heart surgery or aortic valve dysfunction, left bundle branch block may occur.
Introduction: It is due to a defect in the conduction system of left bundle branch leading to delay or blockade of along the pathway that electrical impulses travel to make the ventricles to beat.
Aims and objectives
·         To find out the percentage of people developing LBBB.
·         To find out the relationship of age and coronary artery disease leading to LBBB.
·         To find out the survival of LBBB in various age groups.
Methodology: We obtained the data of 294 patients from Rahman Hospital using a questionnaire and evaluated it using SPSS software. The data was gathered according to inclusion and exclusion criteria that determined whether a major cardiac condition like CAD was present or not. Subsequently, SPSS conducted an analysis of the data and determination was drawn.
Results and Conclusion: Patients identified and studied were 297 and followed for 5 years, the study revealed that 14 percent of patients had age less than 29, 21.4 % of patients having LBBB were around age 30 to 40 years, 26.9% people of CVD had LBBB aged 50-60 years and people above 60 years having CVD had 32.2% LBBB showing that with increase in age of patient having CVD there is more risk of developing LBBB significantly. The LBBB being carrying poor prognosis, the patients were followed for 5 years, revealed that 40 out of 297 (13%) lived for 6 months, 72 out of 297 (25%) lived for 1 year approximately, 44 out of 297 (15%) lived for more than 2 years, approximately 78 out of 297 lost to follow up or died from another cause shown in the graph, which explains that approximately half of patient dies in the first 6 months of diagnosis, so this has to be taken serious and treated adequately. This research gives us a thorough foundation for comprehending how age and cardiac anomalies interact, allowing for early risk assessment of individuals and a decrease in the disease-to-ratio ratio. This initiative helps us lower risk factors, enhance the local health system, and improve patient lives by promoting routine monitoring. 
 
Keywords: 
Left bundle branch block; Coronary artery disease; Cardiomyopathies; Heart blocks
 
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