Profile of Stevens-Johnson syndrome and toxic epidermal necrolysis patients in the inpatient hospital installation of Dr. Soetomo general hospital Surabaya from January 2019 – December 2021
1 Faculty of Medicine, Airlangga University, Surabaya, Indonesia.
2 Department of Dermatology and Venereology, Faculty of Medicine, Airlangga University, Surabaya, Indonesia.
3 Department of Dermatology and Venereology, Faculty of Medicine, Airlangga University, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
4 Department of Dermatology and Venereology, Faculty of Medicine, Airlangga University, Airlangga University Teaching Hospital, Surabaya, Indonesia.
5 Department of Public Health & Preventive Medicine, Faculty of Medicine, Airlangga University, Surabaya, Indonesia.
Research Article
World Journal of Advanced Research and Reviews, 2023, 19(03), 1453–1469
Article DOI: 10.30574/wjarr.2023.19.3.1997
Publication history:
Received on 16 August 2023; revised on 26 September 2023; accepted on 28 September 2023
Abstract:
Background: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis are significant health issues due to their severe complications. Factors like age, clinical symptoms, and underlying etiology play crucial roles in patient management. Therefore, it is important to review further the background or profile of the patients. This is the basis for conducting this study. This research aims to provide an overview of patients with SJS-TEN in the Inpatient Installation of RSUD Dr. Soetomo Surabaya, aiming to aid in prevention and management.
Aim: Providing an overview of the profile of patients with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in the Inpatient Installation of Dr. RSUD. Soetomo Surabaya
Methods: The study analyzed medical records of patients with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis at RSUD Dr. Soetomo Surabaya from 2019-2021, analyzing parameters such as gender, age, symptoms, etiology, comorbidities, and length of stay.
Results: The study found 28 cases of SJS-TEN, with 15 males (53.6%) and 13 females (46.4%). The highest prevalence was in the age group 19-44 years old as we called adult (35.7%). Most patients had multiple comorbidities, with common clinical symptoms including palpebral edema, multiple erythematous macules, conjunctival erythema, and fever. Most patients were classified as SCORTEN 1, with 71.4% taking multiple drugs. Most patients experienced multiple complications but experienced improvement and continued treatment through outpatient care (57.1%).
Keywords:
Stevens-Johnson Syndrome; Toxic Epidermal Necrolysis; SCORTEN; Profile of SJS-TEN Patients; Human & Medicine; Human & Mortality; Immunology
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0