The prevalence of leukocyte abnormalities among Sudanese patients with sickle cell disease
1 Faculty of Medical Laboratory Science, Department of Hematology, University of Kordofan, El-Obeid, Sudan.
2 Faculty of Medicine, Department of Pathology, University of Kordofan, El-Obeid, Sudan.
3 Sharjah Municipality, Department of Public Health Clinic, Sharjah- United Arab Emirates.
Research Article
World Journal of Advanced Research and Reviews, 2021, 09(01), 262-267
Article DOI: 10.30574/wjarr.2021.9.1.0026
Publication history:
Received on 15 January 2021; revised on 22 January 2021; accepted on 24 January 2021
Abstract:
Sickle cell disease (SCD) is an inherited blood disorder that affects red blood cells. The study was conducted in Elobied town during the period May 2011 to September 2011. The aim of this study is to detect the abnormalities of leucocytes among sickle cell anemic patients. 40 sickle cell anemic patients; age range between 8 months to 23 years. Blood sample was taken for all patients and the laboratory investigation were performed using automated estimation for: hemoglobin (Hb), Packed cell volume (PCV), red cell count (RBCs), mean cell volume (MCV), mean cell hemoglobin (MCH), mean cell concentration (MCHC), and total white blood cells, comment on blood film using manual methods. The conclusion of this study there is increase in total white blood cells with shift to left in neutrophil precursor in sickle cell patients with complications ,the most immature cells are band form, myelocytes and metamyelocytes, and there also lymphocytosis and neutrophilia which has been increases in response to infections.
Keywords:
Leukocyte abnormalities ; SCD ; Sudanese patients; CBC
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Copyright © 2021 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0