Prevalence and determinants of hepatitis B virus infection among human immunodeficiency virus patients at a tertiary health care facility in Central Nigeria
Department of Microbiology, Nasarawa State University, P.M.B. 1022, Keffi, Nigeria.
Research Article
World Journal of Advanced Research and Reviews, 2020, 06(02), 227-233
Article DOI: 10.30574/wjarr.2020.6.2.0133
Publication history:
Received on 30 April 2020; revised on 22 May 2020; accepted on 24 May 2020
Abstract:
Hepatitis B virus (HBV) co-infection with human immunodeficiency virus is a major public health problem especially in developing countries. In this study, the prevalence of HBV infection was evaluated among 400 consenting HIV patients accessing healthcare in Federal Medical Center, Keffi, Nigeria using HBsAg detection as the surrogate. Blood samples were collected and screened for HBsAg using ACON screening kit (ACON Laboratories Inc, USA). The Chi-square statistical test was performed to identify possible determining factors associated with the viral infection. Overall, 30 (7.5%) of the participants were reactive to HBsAg. The possible determining factors for acquiring the virus recorded in this study were marital status and alcoholism (p<0.05). Gender, age, educational status, occupation, history of blood transfusion, locality, cigarette smoking, self-manicure and pedicure, tribal marks, tattoos and history of HBV vaccination were not significantly associated with acquiring the viral infection (p>0.05). This finding calls for a concern because co-infection of HBV with HIV accelerates disease progression and also has an effect on the management of patients infected with HIV.
Keywords:
Hepatitis B surface antigen; HIV; Co-infection; Nigeria
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Copyright © 2020 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0