Pituitary macroadenoma revealing Hashimoto’s thyroiditis: When peripheral biology rectifies central imaging!

O. El Gharnati; M. Maouelainin; Pr. H. El Jadi

doi:10.30574/wjarr.2025.28.2.3791

eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 || CrossRef DOI

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Pituitary macroadenoma revealing Hashimoto’s thyroiditis: When peripheral biology rectifies central imaging!

O. El Gharnati ^{1, 2, *}, M. Maouelainin ^{2, 3} and Pr. H. El Jadi ^{1, 4}

¹Department of Endocrinology, Oued Eddahab Military Hospital, Agadir, Morocco.

² Faculty of Medicine and Pharmacy, Ibn Zohr University, Agadir, Morocco.

³ Radiology Department, Oued Eddahab Military Hospital, Agadir, Morocco.

⁴ Faculty of Medicine and Pharmacy, Cadi Ayyad University, Marrakech, Morocco.

Case Report

World Journal of Advanced Research and Reviews, 2025, 28(02), 922-924

Article DOI: 10.30574/wjarr.2025.28.2.3791

DOI url: https://doi.org/10.30574/wjarr.2025.28.2.3791

Publication history

Received on 17 September 2025; revised on 08 November 2025; accepted on 10 November 2025

Abstract

Background: Pituitary macroadenoma is often confused with pituitary hyperplasia, a benign proliferation of thyrotropic cells due to prolonged peripheral hypothyroidism.

Case Presentation: We report the case of a 17-year-old female initially diagnosed with a pituitary macroadenoma, in whom we concluded that pituitary hyperplasia was secondary to Hashimoto’s thyroiditis.

Conclusion: Differential diagnosis is essential to avoid unnecessary surgery, as hormone replacement therapy can lead to complete regression of the mass.

Keywords

Pituitary Hyperplasia; Hashimoto’s Thyroiditis; Hypothyroidism; MRI; Endocrinology

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How to cite this article

O. El Gharnati, M. Maouelainin and Pr. H. El Jadi. Pituitary macroadenoma revealing Hashimoto’s thyroiditis: When peripheral biology rectifies central imaging!. World Journal of Advanced Research and Reviews, 2025, 28(2), 922-924. Article DOI: https://doi.org/10.30574/wjarr.2025.28.2.3791

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Pituitary macroadenoma revealing Hashimoto’s thyroiditis: When peripheral biology rectifies central imaging!

O. El Gharnati ^{1, 2, *}, M. Maouelainin ^{2, 3} and Pr. H. El Jadi ^{1, 4}

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Pituitary macroadenoma revealing Hashimoto’s thyroiditis: When peripheral biology rectifies central imaging!

O. El Gharnati 1, 2, *, M. Maouelainin 2, 3 and Pr. H. El Jadi 1, 4

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O. El Gharnati ^{1, 2, *}, M. Maouelainin ^{2, 3} and Pr. H. El Jadi ^{1, 4}