Pituitary macro adenoma presenting as severe hyponatremia: A case report
Department of Endocrinology, Diabetes, Metabolic Diseases and Nutrition, Mohammed VI University Hospital, Marrakech, Morocco
Case Study
World Journal of Advanced Research and Reviews, 2022, 16(03), 135-137
Article DOI: 10.30574/wjarr.2022.16.3.1317
Publication history:
Received on 26 October 2022; revised on 30 November 2022; accepted on 03 December 2022
Abstract:
Hyponatremia in panhypopituitarism is multifactorial, it can be explained by the corticotropic deficit observed in pituitary insufficiency which is responsible for a lifting of inhibition on the anti-diuretic hormone with a consequent net reduction of water excretion, Hypothyroidism is also cited as a contributing mechanism for the development of acute hyponatremia in pituitary insufficiency through reduced free water excretion. Hyponatremia as a mode of revelation remains rare, we report a case of severe hyponatremia revealing pituitary insufficiency on pituitary macroadenoma.
Keywords:
Hyponatremia; Macroadenoma; Corticotropic defecit; Hypothyroidism; Panhypopituitarism
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