Phytochemical screening and evaluation of the antioxidant activity of the leaves and root barks of Dichrostachys cinerea L. Wight and Arn. (Fabaceae): A plant traditionally used for the treatment of asthma in Korhogo
1 Department of Mathematics-Physics-Chemistry, UFR of Biological Sciences, Peleforo GON COULIBALY University, BP 1328 Korhogo, Côte d'Ivoire.
2 Matter Constitution and Reaction Laboratory, UFR Sciences of the Structures of Matter and Technology, University Félix HOUPHOUËT- BOIGNY, 22 BP 582 Abidjan 22, Côte d’Ivoire.
3 Department of Plant Biology, UFR Biological Sciences, Peleforo GON COULIBALY University, Korhogo, BP 1328 Côte d'Ivoire.
Research Article
World Journal of Advanced Research and Reviews, 2023, 20(01), 127–134
Article DOI: 10.30574/wjarr.2023.20.1.2007
Publication history:
Received on 20 August 2023; revised on 01 October 2023; accepted on 04 October 2023
Abstract:
Dichrostachys cinerea is a plant species with multiple therapeutic uses. The present work focuses on the pharmacological and chemical valorization of the leaves and root barks of this species, harvested in Korhogo (Côte d'Ivoire), for the treatment of asthma. Plant antioxidants could alleviate the symptoms of this pathology. A hydro-ethanol extraction of these organs was carried out by maceration. From the extracts obtained, a phytochemical study in tubes and by TLC revealed the presence of flavonoids, tannins, phenolic acids, saponins, sterols and terpenes in these organs. In addition, the leaves contain coumarins and the root barks alkaloids. Antioxidant activity against the DPPH radical was demonstrated by tube, TLC and spectrophotometric methods. The IC50s of the hydro-ethanol extracts determined showed that the antioxidant power of the leaves (0.06894 mg/mL) is much greater than that of the root barks (0.11147 mg/mL). These results could justify the use of these organs in the traditional treatment of diseases linked to oxidative stress, but particularly asthma. However, further work is required to evaluate the toxicity and antispasmodic effect of these two organs on asthma.
Keywords:
Dichrostachys cinerea; Asthma; Phytochemical screening; Antioxidant activity
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