Phytochemical profiling of Moongiluppathi Chooranam (MC) a traditional polyherbal formulation with special reference in the management of polydipsia in Mathumegam (Diabetes mellitus)

Moongiluppathi Chooranam (MC), a classical polyherbal Siddha formulation mentioned in the Siddha literature “Sikicharatnadeepam” used in the management of polydipsia in Diabetes Mellitus. As per the siddha literature the Moongiluppathi chooranam is indicated for sayathil undagum mega allai and polydipsia in MATHUMEGAM. Out of these two, MC was screened through Preliminary phytochemical profiling for polydipsia in MATHUMEGAM revealed the presence of saponins, tannins, phenols, terpenoids, alkaloids, flavonoids, glycosides, and carbohydrates. High-Performance Thin Layer Chromatography (HPTLC) analysis was performed as per standard guidelines using the solvent system Toluene: Ethyl acetate: Methanol (5:2.5:0.1), and the chromatograms were documented at 254 nm, 366 nm, and 575 nm post-derivatization. Major phytoconstituents identified included gallic acid derivatives, ellagic acid, quercetin, kaempferol glycosides, and coumarin-like terpenoids. The presence of these phytochemicals supports the traditional claims of MC in managing conditions like diabetes, oxidative stress, and liver disorders. The findings establish a scientific basis for the MC formulation’s efficacy and provide a reference fingerprint for quality control and standardization.