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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in March 2026 (Volume 29, Issue 3) Submit manuscript

Phytochemical analysis and antibacterial activities of aqueous and ethanolic crude extracts of soursop (Annona muricata) leaves against selected clinical pathogens

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  • Phytochemical analysis and antibacterial activities of aqueous and ethanolic crude extracts of soursop (Annona muricata) leaves against selected clinical pathogens

Funmi Agnes AJAYI *, Falilat Toyin AKINRULI and Samuel Olalekan FABUNMI

Microbiology Unit, Department of Science Technology, Federal Polytechnic, P.M.B. 5351, Ado-Ekiti, Ekiti State, Nigeria.
 
Research Article
World Journal of Advanced Research and Reviews, 2022, 15(01), 353-359
Article DOI: 10.30574/wjarr.2022.15.1.0681
DOI url: https://doi.org/10.30574/wjarr.2022.15.1.0681
 
Received on 02 June 2022; revised on 16 July 2022; accepted on 18 July 2022
 
This study investigates phytochemical composition and the antimicrobial activities of aqueous and ethanol extracts of soursop (Annona muricata) leaves against some selected bacterial pathogens. Susceptibility effects of these extracts were determined by disc diffusion method against Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Streptococcus pyogenes and Staphylococcus aureus. The results showed that the efficacy of the aqueous extracts was more pronounced against the test bacterial, especially P. aeruginosa at minimum inhibitory concentration (MIC) of 0.2 mg/mL. The ethanol extract was more pronounced again S. pyogenes with diameter of zones of inhibition ranging from 15.00 – 32.00 mm at concentrations of 0.2 – 0.8 mg/mL respectively. The pathogens were susceptible to the aqueous extracts of the leave at concentrations between 0.4 – 0.8 mg/mL. Phytochemical compounds such as tannins, saponins, terpenoids, alkaloids, glycosides, and phenols were detected in A. muricata leaf extract. The significant antimicrobial properties of the leaf extract could be attributed to the presence of these bioactive compounds. Thus, this investigation proves to an extent that the Soursop leaf extracts when used against microorganisms, has sufficient antimicrobial property.
 
Annona muricata; Antibacterial; Clinical pathogens; Crude extracts; Phytochemical
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2022-0681.pdf

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Funmi Agnes AJAYI, Falilat Toyin AKINRULI and Samuel Olalekan FABUNMI. Phytochemical analysis and antibacterial activities of aqueous and ethanolic crude extracts of soursop (Annona muricata) leaves against selected clinical pathogens. World Journal of Advanced Research and Reviews, 2022, 15(1), 353-359. Article DOI: https://doi.org/10.30574/wjarr.2022.15.1.0681

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