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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in April 2026 (Volume 30, Issue 1) Submit manuscript

Peripheral hypothyroidism and TAFRO syndrome: Particularity of management

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  • Peripheral hypothyroidism and TAFRO syndrome: Particularity of management

CAMARA M’BALLOU *, MENNANI FATIMA EZZAHRA, BOUKHALFA AHMED, RAFI SANA, El MGHARI GHIZLANE and El ANSARI NAWAL

Department of Endocrinology Diabetology and Metabolic Diseases, PCIM Laboratory, FMPM, Cadi Ayyad University, CHU Mohamed VI Marrakech.
 
Case Study
World Journal of Advanced Research and Reviews, 2023, 17(02), 742-744
Article DOI: 10.30574/wjarr.2023.17.2.0300
DOI url: https://doi.org/10.30574/wjarr.2023.17.2.0300
 
Received on 09 January 2023; revised on 20 February 2023; accepted on 22 February 2023
 
TAFRO syndrome is defined by the presence of thrombocytopenia, hydrops, fever, fibrosis, renal dysfunction, and organomegaly and can be seen with idiopathic multicentric Castleman disease (iMCD) or as an isolated process without iMCD. The pathophysiology of TAFRO is not well understood, but it is thought to be related to hypercytokinemia. Subclinical hypothyroidism may be a potential factor in the pathogenesis and symptomatology of TAFRO syndrome with elevated vascular endothelial growth factor (VEGF).There are no clear guidelines for the treatment of TAFRO in the absence of a definitive diagnosis of iMCD, resulting in suboptimal management and high morbidity. We report a case of hypothyroidism revealed by TAFRO syndrome.
 
Hypothyroidism; TAFRO syndrome; VEGF; Management
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2023-0300.pdf

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CAMARA M’BALLOU, MENNANI FATIMA EZZAHRA, BOUKHALFA AHMED, RAFI SANA, El MGHARI GHIZLANE and El ANSARI NAWAL. Peripheral hypothyroidism and TAFRO syndrome: Particularity of management. World Journal of Advanced Research and Reviews, 2023, 17(2), 742-744. Article DOI: https://doi.org/10.30574/wjarr.2023.17.2.0300

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