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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in March 2026 (Volume 29, Issue 3) Submit manuscript

Oral Biofilms: A literature review on composition, development and clinical implications in dental health

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  • Oral Biofilms: A literature review on composition, development and clinical implications in dental health

Lunetta Violla Shalshabilla * and Mutiara Puspita Hermawan

Undergraduate Student, Faculty of Dental Medicine, Universitas Airlangga, Surabaya 60132, Indonesia.

Review Article

World Journal of Advanced Research and Reviews, 2025, 28(02), 391-394

Article DOI: 10.30574/wjarr.2025.28.2.3734

DOI url: https://doi.org/10.30574/wjarr.2025.28.2.3734

Received on 20 September 2025; revised on 02 November 2025; accepted on 04 November 2025

Objectives: This article aims to discuss the composition of oral biofilms, their developmental stages, and the implications of biofilms for dental health, particularly in relation to caries and periodontal disease.

Methods: The research method used was a literature review using PubMed, Scopus, and ScienceDirect databases with keywords "oral biofilm," "composition," "dental caries," and "periodontal disease'.' The selected articles were published from 2015 to 2024.

Results: Oral biofilms are composed of complex microbial communities, including Streptococcus mutans, Actinomyces, Lactobacillus, and anaerobic bacteria. There are four stages of biofilm formation: pellicle formation, initial colonization, co-aggregation, and maturation. Biofilms play a significant role in the pathogenesis of caries through acid production and enamel demineralization, as well as in periodontitis through the inflammation of periodontal tissues.

Conclusion: Understanding the composition and dynamics of oral biofilms is essential for the prevention of dental disease. Intervention strategies include oral hygiene, fluoride use, probiotics, and the latest antibiofilm technologies.

Oral Biofilm; Dental Caries; Periodontal Disease; Oral Microbiome; Dental Plaque

https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2025-3734.pdf

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Lunetta Violla Shalshabilla and Mutiara Puspita Hermawan. Oral Biofilms: A literature review on composition, development and clinical implications in dental health. World Journal of Advanced Research and Reviews, 2025, 28(2), 391-394. Article DOI: https://doi.org/10.30574/wjarr.2025.28.2.3734

Copyright © Author(s). All rights reserved. This article is published under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits use, sharing, adaptation, distribution, and reproduction in any medium or format, as long as appropriate credit is given to the original author(s) and source, a link to the license is provided, and any changes made are indicated.


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