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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in April 2026 (Volume 30, Issue 1) Submit manuscript

Oleanolic acid as a potential drug molecule: A review

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  • Oleanolic acid as a potential drug molecule: A review

Manisha H Vite *, Mayuri I Sonawane and Prathmesh M Vayal

Shivajirao S Jondhle college of Pharmacy, Asangaon, Thane 421601, Maharashtra, India.
 
Review Article
World Journal of Advanced Research and Reviews, 2023, 17(01), 249-254
Article DOI: 10.30574/wjarr.2023.17.1.1469
DOI url: https://doi.org/10.30574/wjarr.2023.17.1.1469
 
Received on 25 November 2022; revised on 05 January 2023; accepted on 07 January 2023
 
Objective: Oleanolic acid is traditionally used medicinal remedies in India. Oleanolic acid or oleanic acid is a naturally occurring pentacyclic triterpenoid related to betulinic acid. It is widely distributed in food and plants where it exists as a free acid or as an aglycone of triterpenoid saponins.
Key findings: Oleanolic acid is relatively non-toxic, hepatoprotective, and exhibits antitumor and antiviral properties. It was found to exhibit weak anti-HIV and weak anti-HCV activities in vitro, but more potent synthetic analogs are being investigated as potential drugs.
Conclusion: This review is an overall overview of the existing pharmacology of Oleanolic acid, helping to fuel further research in the various unexplored activities that are attributable to this plant.
 
Oleanolic acid; Hepatoprotective; Antitumor; Antiviral; Antibacterial
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2022-1469.pdf

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Manisha H Vite, Mayuri I Sonawane and Prathmesh M Vayal. Oleanolic acid as a potential drug molecule: A review. World Journal of Advanced Research and Reviews, 2023, 17(1), 249-254. Article DOI: https://doi.org/10.30574/wjarr.2023.17.1.1469

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