Obesity and chronic kidney disease: What specificity of this association and what epidemiological profile? A prospective study
Endocrinology Department, Avicenna Military Hospital, Faculty of Medicine and Pharmacy, Cadi Ayyad University -Marrakech, Morocco.
Research Article
World Journal of Advanced Research and Reviews, 2024, 21(02), 293–300
Publication history:
Received on 24 December 2023; revised on 03 February 2024; accepted on 05 February 2024
Abstract:
Obesity is accompanied by chronic diseases including cardiometabolic diseases. Obesity is also an independent factor of renal risk that deserves to be taken into account. The aims of our work were to determine the prevalence of chronic kidney disease related to obesity independently of all other usual risk factors and to describe its epidemiological characteristics in our population.
We conducted a prospective descriptive and analytic study over a period of 12 months in 38 patients over 18 years of age, with a BMI> 30 Kg / m² and without diabetes, hypertension, or other apparent cause chronic kidney disease, collected at the consulting service of the Military Hospital Avicenna of Marrakech, Morocco.
The average age of our patients was 38 years with a female predominance (sex ratio (m/w) of 0.80). The average BMI was 35.35 kg / m². Dyslipidemia was found in 68.42% of patients, hyperuricemia in 18.42%, microalbuminuria in 13.15%, macroalbuminuria in 7.89% and hematuria in 2.6%. Glomerular hyperfiltration was present in 13.15% of cases and no patient had a GFR <60 ml / min / 1.73m². The prevalence of chronic kidney disease among obese people in our population was 10.5%. Older obese patients with high BMI, hypertriglyceridemia, hypercholesterolemia, and hyper LDLemia were the most affected, with statistically significant differences between the 2 groups of patients with and without chronic kidney disease (P <0.05).
Our study warn of the need for cost-effective and well-adapted prevention measures to reverse the growing epidemic of obesity in the world.
Keywords:
Obesity; Chronic kidney disease; Epidemiology; Risk factors
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