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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in April 2026 (Volume 30, Issue 1) Submit manuscript

Niemann-Pick Type B long taken for miliary tuberculosis: A Rare cause of interstitial lung disease: A case report

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  • Niemann-Pick Type B long taken for miliary tuberculosis: A Rare cause of interstitial lung disease: A case report

Mohamed Ijim 1, *, Salma Ait Batahar 1, Sara Kechnaoui 1, Imane Saidi 1, Lamyae Amro 1, Latifa Elouazani 2 and Fatima Ezzahra Hazmiri 2

1 Department of Pulmonology, Mohammed VI university hospital center, LRMS Lab, FMPM, Cadi Ayyad University, Marrakech, Morocco.
2 Department of Pathology,Mohammed VI university hospital center, LRMS Lab, FMPM, Cadi Ayyad University, Marrakech, Morocco.
Case Study
World Journal of Advanced Research and Reviews, 2023, 19(02), 261-267
Article DOI: 10.30574/wjarr.2023.19.2.1512
DOI url: https://doi.org/10.30574/wjarr.2023.19.2.1512
Received on 19 June 2023; revised on 24 July 2023; accepted on 27 July 2023
Background: Type B Niemann-Pick disease (NPD) is a rare lysosomal storage disease secondary to a deficiency in sphingomyelinase activity. The accumulation of sphingomyelin occurs in various organs, the lung in particular, the involvement of which determines the prognosis of the disease [1].
Case presentation: We report a case of type B NPD disease diagnosed in adolescence who was mistakenly treated as a miliary tuberculosis. The disease was revealed by a dyspnea, with a diffuse interstitial disease and a crazy paving at the chest computed tomography, and many foamy histiocytes with finely vacuolated cytoplasm on the bronchoalveolar lavage.
Conclusion: Through this case, we underline the diagnostic difficulty of type B NPD and we recall the elements of orientation towards this pathology.
Lysosomal storage disorder; Interstitial pulmonary disease; Niemann pick type B; Case report
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2023-1512.pdf

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Mohamed Ijim, Salma Ait Batahar, Sara Kechnaoui, Imane Saidi, Lamyae Amro, Latifa Elouazani and Fatima Ezzahra Hazmiri. Niemann-Pick Type B long taken for miliary tuberculosis: A Rare cause of interstitial lung disease: A case report. World Journal of Advanced Research and Reviews, 2023, 19(2), 261-267. Article DOI: https://doi.org/10.30574/wjarr.2023.19.2.1512

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