Neurotransmitters and nitric oxide are released in various brain areas according to ultradian and infradian rhythms

Athineos Philippu *

Department of Pharmacology and Toxicology, University of Innsbruck, Austria.
 
Mini-review
World Journal of Advanced Research and Reviews, 2020, 08(02), 233-236
Article DOI: 10.30574/wjarr.2020.8.2.0430
 
Publication history: 
Received on 13 November 2020; revised on 20 November 2020; accepted on 21 November 2020
 
Abstract: 
The push-pull superfusion technique was used to investigate release of endogenous neurotransmitters and nitric oxide in various brain regions. The transmitters catecholamines, histamine, GABA, glutamate, as well and nitric oxide are released according to ultradian rhythms which generate fluctuations of vegetative functions such as blood pressure and arousal. More frequent infradian oscillations of neurotransmitter and nitric oxide release fates are implicated in mutual interneural control. 
 
Keywords: 
Push-pull superfusion; Ultradian and infradian oscillations; Neurotransmitter release; Nitric oxide; Blood pressure; arousal
 
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