Neuroendocrine carcinoma of the nasal cavity and paranasal sinuses: A case report and literature review

Driss Elidrissi 1, *, Omar Oulghoul 1, Omayma bourht 1, Mohamed Chehbouni 1, Youssef Lakhdar 1, Othmane Benhoummad 2, Youssef Rochdi 1 and Abdelaziz Raji 1

1 Department of ENT and HNS Surgery, Mohammed VI University Hospital, Marrakech, Morocco.
2 Department of ENT and HNS Surgery, Faculty of Medicine and Pharmacy of Agadir, Ibn Zohr University, Agadir, Morocco.
 
Case Study
World Journal of Advanced Research and Reviews, 2024, 24(02), 2259–2264
Article DOI10.30574/wjarr.2024.24.2.3553
 
Publication history: 
Received on 11 October 2024; revised on 22 November 2024; accepted on 25 November 2024
 
Abstract: 
Neuroendocrine tumors are defined as epithelial neoplasms with predominant neuroendocrine differentiation. They can occur in almost any organ of the body. The nasal cavity and paranasal sinuses are a rare site of neuroendocrine carcinoma. Recurrences are frequent, and prognosis is poor. The difficulty of pathological diagnosis and the rarity of this malignancy have hampered progress in understanding the clinical course and improving outcomes. We report a rare case of a neuroendocrine tumor of the nasal cavity and ethmoidal sinuses with invasion of the orbit in a 35-year-old male patient. The literature is reviewed and aetiopathogenic theories, diagnostic procedures and surgical approaches are discussed.
 
Keywords: 
Neuroendocrine Carcinoma; Nasal cavity; Paranasal sinuses; Endoscopic surgery; Radiotherapy
 
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