Neurobiology of Attention Deficit Hyperactivity Disorder (ADHD): A brief review

Marcos Altable 1, *, Emilio Díaz-Moreno 2 and Muhammad Akram 3

1 Department of Neurology. Neuroceuta. (Virgen de África Clinic). Ceuta, Spain.
2 Department of Neuropsychology. Neuroceuta. (Virgen de África Clinic). Ceuta, Spain.
3 Department of Eastern Medicine, Government College University Faisalabad Pakistan.
 
Review Article
World Journal of Advanced Research and Reviews, 2024, 21(02), 1387–1391
Article DOI: 10.30574/wjarr.2024.21.2.0576
 
Publication history: 
Received on 12 January 2024; revised on 19 February 2024; accepted on 21 February 2024
 
Abstract: 
Attention deficit hyperactivity disorder (ADHD) is a common condition associated with long-lasting psychosocial functioning difficulties and high psychiatric morbidity. ADHD is a heterogeneous syndrome in its clinical presentation and probably in its aetiology. Nevertheless, it can be understood as a spectrum of multifactorial cognitive, emotional, and behavioural dysfunctions under the influence of genetic and environmental factors, mainly perinatal. For several decades, the dopaminergic dysfunction hypothesis has been one of the possible pathways in the origin of ADHD. Still, other neurotransmission systems also appear to play a role, as evidenced by the recent therapeutic development of noradrenergic agonists in this indication.
 
Keywords: 
Attention deficit hyperactivity disorder; Pathophysiology; Biology; Genetic; Risk
 
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