Necrotising sarcoid granulomatosis: A report case

H Benaziz *, S Bounhar, M Ijim, O Fikri and L Amro

Faculty of medicine and pharmacy, Caddy Ayyad university, Department of Pulmonary, ARRAZI Hospital, Mohammed VI University hospital center, Marrakech, Morocco.
 
Case Study
World Journal of Advanced Research and Reviews, 2024, 21(03), 1526–1529
Article DOI: 10.30574/wjarr.2024.21.3.0732
 
Publication history: 
Received on 19 January 2024; revised on 05 March 2024; accepted on 07 March 2024
 
Abstract: 
Sarcoidosis is a systemic granulomatous disease characterised by the appearance of noncaseifying epithelioid granulomas in the affected organs, most commonly the lungs, skin, and eyes. Necrotizing sarcoid granulomatosis is challenging to diagnose due to its rarity and similarity with other necrotizing disorders. We describe a case of a 47-year male with fever, chest pain, and nodular pulmonary opacities on chest radiograph. Histological examination of the lung tissue confirmed NSG. Diagnostically, infectious causes, vasculitis, and malignancy were excluded. A corticosteroid treatment has been started with a tendency to regression. The key to diagnosis, emphasized in our paper, is the histopathological finding. The course of NSG is similar to sarcoidosis. The treatment of choice is Corticosteroids, but the disease exhibits a tendency towards spontaneous regression. 
 
Keywords: 
Necrotizing; Sarcoid; Granulomatosis; Caseous necrosis; rare entity; Differentiation diagnosis
 
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