Mandibular changes in a patient suspected with Thalassemia trait: A case report by radiograph finding

Annisa Putri 1, *, Ernita Sari 2 and Yolanda Kartika Asmarani 3

1 Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Institute Ilmu Kesehatan Bhakti Wiyata, Kediri, Indonesia, 64114.
2 Department of Oral Biology, Faculty of Dentistry, Institute Ilmu Kesehatan Bhakti Wiyata, Kediri, Indonesia, 64114.
3 Department of Oral Pathology, Faculty of Dentistry, Institute Ilmu Kesehatan Bhakti Wiyata, Kediri, Indonesia, 64114.
 
Case Study
World Journal of Advanced Research and Reviews, 2024, 21(01), 1775–1779
Article DOI: 10.30574/wjarr.2024.21.1.0240
 
Publication history: 
Received on 10 December 2023; revised on 17 January 2024; accepted on 19 January 2024
 
Abstract: 
Thalassemia is an inherited hemolytic anemia characterized by abnormal synthesis the hemoglobin globin component. A forty-year-old woman presented to a private dentist complaining of a left-sided facial pain and headache that occurred out of the blue. Panoramic radiograph showed severe caries on several teeth, generalized reduction in the alveolar crest, thin lamina dura and changes in trabecular pattern of mandible and the inferior alveolar canal on each side was partially absent. Unmanaged anemia caused ineffective erythropoiesis resulting extensive bone marrow with sparse coarse trabecular. As the mean hemoglobin falls, enhanced osteoclastic bone resorption thus thinning lamina dura, reducing alveolar crest and lacking radiopaque line of inferior alveolar canal. Panoramic is widely used in dentistry, this case report presents a case of patient discovered thalassemia through radiological findings.
 
Keywords: 
Thalassemia; Oral manifestation; Radiograph; Panoramic
 
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