Liposome assisted drug delivery-A review
Department of Oral Medicine and Radiology Sree Anjaneya Institute of Dental Sciences Modakkallur, Atholi, Calicut.
Research Article
World Journal of Advanced Research and Reviews, 2021, 12(03), 594–601
Article DOI: 10.30574/wjarr.2021.12.3.0739
Publication history:
Received on 22 November 2021; revised on 28 December 2021; accepted on 30 December 2021
Abstract:
Liposomes, sphere-formed vesicles consisting of one or greater phospholipid bilayers, had been first described within the mid-60s. Among numerous gifted new drug delivery systems, liposomes signify an advanced generation to supply active molecules to the site of action, and right now, numerous formulations are in clinical use.
The application of liposomes to help drug shipping has already had a chief impact on many biomedical regions. They have been proven to be beneficial for stabilizing pharmaceuticals, overcoming boundaries to cellular and tissue uptake, and improving biodistribution of compounds to goal sites In vivo. This permits powerful delivery of encapsulated compounds to goal sites even as minimizing systemic toxicity. Liposomes present as an attractive transport gadget due to their wide physicochemical and biophysical properties which allow smooth manipulation to cope with exclusive shipping concerns. In this review, we will talk the advances in liposome assisted drug shipping, biological challenges, and present day medical and experimental use of liposomes for biomedical applications. The translational limitations of liposomal technology may also be provided.
Keywords:
Liposome; Drug delivery; Reticuloendothelial system; Opsonisation
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Copyright © 2021 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0