Juju Jam: Natural anti-cancer food from Bidara fruit for cancer risk patients

Izzaz Prawira Wicaksono 1, *, Muhammad Nadhiv Basalamah 1, Danendra Reyhan Kesuma 1, Ahnaf Zachary Indrasta 1, Muhammad Zufar Putra Ferian 1 and Nur Chamimmah Lailis Indriani 2

1 Department of Mathematics and Science, Al Hikmah Senior High School, Surabaya, East Java, Indonesia.
2 Department of Chemistry, Sepuluh Nopember Institute of Technology, Surabaya, East Java, Indonesia.
 
Research Article
World Journal of Advanced Research and Reviews, 2023, 17(03), 800–808
Article DOI: 10.30574/wjarr.2023.17.3.0490
 
Publication history: 
Received on 16 February 2023; revised on 22 March 2023; accepted on 24 March 2023
 
Abstract: 
Cancer is the second leading cause of mortality worldwide, responsible for one in six deaths. Conventional treatments have been advancing and becoming more effective, but scientists continue to seek alternative and complementary treatments. Nature is the main source of alternative medicine for various diseases, including cancer. For example, mineral-rich plants are widely available in Indonesia and have been used traditionally to treat illnesses. One of them is the bidara fruit (Ziziphus mauritiana), which has medicinal compounds such as flavonoid, phenolic and tannin. The 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) antioxidant assay test shows an IC50 234,2139 ppm and classifies bidara fruit extract as a medium antioxidant. Meanwhile, the Brine Shrimp Lethality Test (BSLT) test shows an LC50 4,5449 and classifies bidara fruit extract as having high toxicity.
 
Keywords: 
Bidara Fruit; Antioxidant; Antibacterial; Anti-Cancer; Flavonoid; Extract
 
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