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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in March 2026 (Volume 29, Issue 3) Submit manuscript

The investigation of toxic, genotoxic and cytotoxic effects of various nanoparticles in Allium cepa and Caenorhabditis elegans test systems

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  • The investigation of toxic, genotoxic and cytotoxic effects of various nanoparticles in Allium cepa and Caenorhabditis elegans test systems

Atacı Gamze and Türkoğlu Şifa*

Cumhuriyet University, Faculty of Science, Deparment of Biology, Sivas Turkey.
 
Research Article
World Journal of Advanced Research and Reviews, 2020, 05(01), 016-035
Article DOI: 10.30574/wjarr.2020.5.1.0108
DOI url: https://doi.org/10.30574/wjarr.2020.5.1.0108
 
Received on 16 December 2019; revised on 07 January 2020; accepted on 09 January 2020
 
In this study, toxic, genotoxic and cytotoxic effects of titanium dioxide (TiO2), silicon oxide (SiO2), zinc oxide (ZnO), copper oxide (CuO) and aluminium oxide (Al2O3) nanoparticles on Allium cepa (A. cepa) and Caenorhabditis elegans (C. elegans) model organisms were investigated. 25, 50, and 100 µg/ml doses of these substances were applied to A. cepa roots for 12 and 24 hours. At the end of the study, it was determined that mitotic index decreased and chromosomal abnormalities occurred. As a result of the application doses of these substances to C. elegans nematode, survival time decreased, egg production decreased and physical growth decreased.
 
Nanoparticle; Allium cepa; Caenorhabditis elegans; Genotoxic effect; Toxicology
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2019-0108.pdf

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Atacı Gamze and Türkoğlu Şifa. The investigation of toxic, genotoxic and cytotoxic effects of various nanoparticles in Allium cepa and Caenorhabditis elegans test systems. World Journal of Advanced Research and Reviews, 2020, 5(1), 016-035. Article DOI: https://doi.org/10.30574/wjarr.2020.5.1.0108

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