1 Department of Nursing, School of Health Sciences, Cyprus University of Technology, 30 Arch. Kyprianos Str., CY-3036, Limassol, Cyprus.
2 Department of Obstetrics, Iasis Private Hospital, 8 Voriou Ipirou Str., CY-8036, Paphos, Cyprus.
3 Department of Midwifery, School of Health and Care Sciences, University of West Attica, 28 Ag. Spyridonos Str., GR-12243, Athens, Greece.
4 Department of Obstetrics and Gynaecology, Aretaieio Hospital, National and Kapodistrian University of Athens, 76 Vasilissis Sofias Str., GR-11528, Athens, Greece.
5 Department of Obstetric Emergency, General and Maternity Hospital “Helena Venizelou”, 2 Elenas Venizelou Str., GR-11521, Athens, Greece.
6 B' Neonatal Intensive Care Unit, Aghia Sophia Children's Hospital, National and Kapodistrian University of Athens, Thivon 1 & Papadiamantopoulou Str., GR-11527, Athens, Greece.
† These authors contributed equally to this work.
Review Article
World Journal of Advanced Research and Reviews, 2023, 19(03), 964-977
Article DOI: 10.30574/wjarr.2023.19.3.1884
Received on 09 August 2023; revised on 17 September 2023; accepted on 19 September 2023
Intraventricular hemorrhage (IVH) is a common complication of premature neonates and according to several authors its prevalence varies between 15% - 44.7%. Numerous perinatal risk factors have been associated with the development of IVH. This hemorrhagic situation has been defined as a leading cause of neonatal morbidity and mortality despite the great improvement observed in the clinical management of premature neonates. Rates of neonatal morbidity and adverse neurologic sequelae due to IVH remain high, making clinical decisions regarding treatment and management of IVH, challenging for healthcare professionals working in Neonatal Intensive Care Units. Since IVH is a complex situation that requires the involvement of a multidisciplinary team, we aimed to provide a comprehensive review of the topic. Through up-to-date scientific data, this review summarizes the key aspects of IVH in relation to development, pathophysiology, diagnosis and management via pharmacological and non-pharmacological approaches.
Intraventricular hemorrhage; Premature neonate; Diagnosis; Pathophysiology; Prevention; Management
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Eleftheria Lazarou, Dimitra Metallinou, Grigorios Karampas, Antigoni Sarantaki, Kleanthi Gourounti, Maria Tigka, Maria Tzeli, Nikoletta Pantelaki, Aikaterini Lykeridou and Christina Nanou. Intraventricular hemorrhage in premature neonates: A narrative review of perinatal risk factors, pathophysiology, diagnosis, prevention and management. World Journal of Advanced Research and Reviews, 2023, 19(3), 964-977. Article DOI: https://doi.org/10.30574/wjarr.2023.19.3.1884