Identifying immunological markers for bowel cancer
Department of Biochemistry Azerbaijan Medical University, Azerbaijan.
Review Article
World Journal of Advanced Research and Reviews, 2023, 20(03), 1731–1733
Article DOI: 10.30574/wjarr.2023.20.3.2670
Publication history:
Received on 17 November 2023; revised on 26 December 2023; accepted on 29 December 2023
Abstract:
The role of immunological processes in the pathophysiology of colorectal cancer has received a lot of attention lately and has been extensively researched. Immune processes are significantly regulated by cytokines and antimicrobial peptides (AMP). Numerous studies have demonstrated the significance of cytokines in the prognosis and surveillance of malignant oncological illnesses. In group II, the blood serum concentration of Calprotectin was found to be greater in 13 patients (92.0%) and lower in 1 patient (8.0%) compared to control limits (χ=24.27, p<0.001). The obtained results show that, in comparison to the control group, the concentration of Calprotectin rises statistically consistently by 3.5 times, with a coefficient of integrity of p<0.001. According to the data, there is a statistically significant rise in Calprotectin concentration (3.5 times higher than in the control group) with a p-value of less than 0.001. The average mathematical density of this indicator is 3.42±0.48 pg/ml, the minimum density is 0.7 pg/ml, and the maximum thickness is 6.1 pg/ml.
Keywords:
Colorectal cancer; Calprotectin; CEA; Antimicrobial peptides
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0