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eISSN: 2582-8185 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in March 2026 (Volume 29, Issue 3) Submit manuscript

Heart shock secondary to the use of clozapine

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  • Heart shock secondary to the use of clozapine

Jorge Andrés Ojeda Villota 1, *, Guillermo David Barros Bohorquez 1, Leonardo José Mier Martínez 2, Lina Marcela Álvarez Vides 3, Martha Lucia Beltran Avilez 2, Andrés Felipe Salas Ramírez 4, John Edinson Pérez Ortega 5 and Guillermo Contento Suescun 6

1 Internist, Universidad Metropolitana de Barranquilla, Colombia.
2 General Physician, Universidad de Sucre, Colombia.
3 General Physician, Universidad Del Sinú, Montería, Colombia.
4 General Physician, Fundación Universitaria Juan N. Corpas, Bogotá, Colombia.
5 General Physician, Universidad Autónoma de Bucaramanga, Colombia.
6 General Physician, Universidad de Boyacá, Colombia.
 
Review Article
World Journal of Advanced Research and Reviews, 2022, 13(03), 104–108
Article DOI: 10.30574/wjarr.2022.13.3.0211
DOI url: https://doi.org/10.30574/wjarr.2022.13.3.0211
 
Received on 01 February 2022; revised on 03 March 2022; accepted on 05 March 2022
 
Clozapine is an exceptionally effective antipsychotic and is approved only for use in refractory schizophrenia due to its adverse effects, including neutropenia, agranulocytosis, seizures, metabolic syndrome, and myocarditis. Cardiogenic shock represents a pathophysiological state where the heart is unable to maintain effective cardiac output (CO) in relation to the metabolic demands of the body, when it is derived from the use of clozapine it is an indirect complication, which occurs secondary to myocarditis due to hypersensitivity to said drug or also other myocardial conditions, myocarditis is an acute inflammatory disorder whose etiology is associated with an infectious process or mediated by an immune response either by drugs or toxins.
 
Clozapine; Cardiogenic Shock; Myocarditis; Drug
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2022-0211.pdf

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Jorge Andrés Ojeda Villota, Guillermo David Barros Bohorquez, Leonardo José Mier Martínez, Lina Marcela Álvarez Vides, Martha Lucia Beltran Avilez, Andrés Felipe Salas Ramírez, John Edinson Pérez Ortega and Guillermo Contento Suescun. Heart shock secondary to the use of clozapine. World Journal of Advanced Research and Reviews, 2022, 13(3), 104-108. Article DOI: https://doi.org/10.30574/wjarr.2022.13.3.0211

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