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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in March 2026 (Volume 29, Issue 3) Submit manuscript

Green metric tools and white assessment in bioanalytical method development and validation: A comprehensive review

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  • Green metric tools and white assessment in bioanalytical method development and validation: A comprehensive review

Sravanthi Gandu, Kumaraswamy Gandla * and Lalitha Repudi

Department of Pharmacy, Chaitanya (Deemed to be university), Gandi pet, Himayath Nagar (Vill), Hyderabad-500075, Telangana, India.

Review Article

World Journal of Advanced Research and Reviews, 2025, 26(03), 1674-1680

Article DOI: 10.30574/wjarr.2025.26.3.2362

DOI url: https://doi.org/10.30574/wjarr.2025.26.3.2362

Received on 07 May 2025; revised on 14 June 2025; accepted on 16 June 2025

The increasing demand for sustainable and eco-friendly practices in pharmaceutical and bioanalytical research has prompted the integration of green chemistry principles into analytical method development. This review discusses the implementation of Green Analytical Chemistry (GAC) metrics, such as Analytical Eco-Scale, Green Analytical Procedure Index (GAPI), and Analytical Greenness (AGREE), as well as the emerging White Analytical Chemistry (WAC) concept, in the development and validation of bioanalytical methods. We highlight the significance, methodology, and applications of these tools in assessing the environmental impact, efficiency, and overall sustainability of bioanalytical procedures. Case studies from recent literature are examined to illustrate practical applications and future directions. 

Green Analytical Chemistry; White Analytical Chemistry; Bioanalytical Methods; Method

https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2025-2362.pdf

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Sravanthi Gandu, Kumaraswamy Gandla and Lalitha Repudi. Green metric tools and white assessment in bioanalytical method development and validation: A comprehensive review. World Journal of Advanced Research and Reviews, 2025, 26(3), 1674-1680. Article DOI: https://doi.org/10.30574/wjarr.2025.26.3.2362

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