Gougerot-Sjögren Syndrome Associated with Hypersensitivity Pneumonitis: Report of Two Cases"

Chronic hypersensitivity pneumonitis (HP) is a rare interstitial lung disease caused by environmental antigen exposure. This report describes two cases of chronic HP associated with Sjögren's syndrome. The first case involved a 55-year-old woman exposed to pigeon droppings, presenting with dyspnea and alveolitis confirmed by bronchoalveolar lavage and positive anti-pigeon antibodies. The second case was a 41-year-old woman exposed to mold, presenting with basal fibrosis and positive anti-SSA/SSB antibodies. Both cases demonstrated salivary gland lymphocytic sialadenitis consistent with Sjögren's syndrome. Treatment included antigen avoidance, corticosteroids, and azathioprine. These cases underscore the importance of thorough diagnostic evaluation and a multidisciplinary approach for optimal management of HP and associated autoimmune diseases.