Global impact of antimicrobial resistance on cancer care: Challenges and strategies in low- and middle-income countries

Alhamdu Dawa Bulus 1, Esther Chidinma Ezeh 1, *, Ritji Victor Goldim 3 and Angela Ene Edache 4

1 Department of Molecular Biology and Genomics, Global Health and Infectious Diseases Control Institute, Nassarawa State University, Keffi Nigeria.
2 Department of Biochemistry, Faculty of Science, Federal University Gashua, Yobe State Nigeria.
3 Laboratory Department, Edoch Medical Services, Jos-South Plateau State, Nigeria.
4 Department of public Health, faculty of Basic and applied Biological science, Ahmadu Bello university Nigeria.
 
Review Article
World Journal of Advanced Research and Reviews, 2024, 23(03), 780–789
Article DOI: 10.30574/wjarr.2024.23.3.2719
 
Publication history: 
Received on 27 July 2024; revised on 02 September 2024; accepted on 05 September 2024
 
Abstract: 
Antimicrobial resistance (AMR) is a fast-rising global health warning that causes significant challenges to the treatment and management of infectious diseases, especially in cancer patients, who are a large number of the vulnerable populations. This work underlines the complicated problems faced by the low- and middle-income countries (LMICs) in cancer care due to AMR. The burden of both cancer and AMR is sadly high, so therefore this review sheds light into the possible potential strategies to win against these challenges and set up better cancer treatment for improved outcomes in these countries. This sheds more light and gives a deeper understanding of recent research works, epidemiological data, and relevant case studies. Furthermore, examining the interconnectivity between AMR and cancer care, narrowing it down to some particular challenges and vulnerabilities encountered by cancer patients in LMICs. The study identifies key strategies such as implementing better antimicrobial stewardship programs, improving infection prevention and control, promoting new drug development, and enhancing global interactions as important steps in reducing the effect of AMR on cancer care in LMICs. This emphasizes the urgent need for targeted interventions, context-specific solutions, building sustainable development, and global interactions to address the complex challenges posed by AMR in cancer care within LMICs.
 
Keywords: 
Antimicrobial resistance; Low- and middle-income countries; Multidrug-resistant; Cancer care
 
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