Fungal skin disorders and their alleviation using Delonix regia extract

Syed Umme Hani 1, *, Mohammed Taufeeque Shaikh 2, *, Ibaadur Rahman Shaikh 3, Safar Abdul Wahab Khan 4, Syed Qanet Ahmed 5, Syed Ammar Ahmed 6, Khwaja Kausar Jabeen 7 and Syed Ather Ahmed 8

1 Department of Science, Roots and Wings Academy, Silicon Valley, Himayat Bagh, Aurangabad (M.S.), India-431002.
2 Department of Science, Supreme Global School, Near Ameen Hospital, Roshan Gate, Aurangabad (M.S.), India-431001.
3 Department of Homeopathy, Shri Prakash Chand Jain Homeopathic Medical College, Palaskhed, Tal. Jamner, Dist. Jalgaon (MS), India-424206.
4 Department of Administration and Management, Roots and Wings Academy, Silicon Valley, Himayat Bagh, Aurangabad (M.S.), India-431002.
5 Department of Secondary Education, Sarosh High School, Padegaon, Aurangabad (M.S.), India-431001.
6 Department of Electronics, National Institute of Electronic and Information Technology, Aurangabad (M.S.), India-431001.
7 Department of Primary Education, Fatema Urdu School, Kiradpura, Aurangabad (M.S.), India-431001.
8 Department of Secondary and Higher Secondary Education, Nemat Urdu School and Junior College, Tal. Khuldabad, Dist. Aurangabad (M.S.), India-431101.
 
Research Article
World Journal of Advanced Research and Reviews, 2024, 24(02), 819–826
Article DOI: 10.30574/wjarr.2024.24.2.3422
 
Publication history: 
Received on 30 September 2024; revised on 05 November 2024; accepted on 08 November 2024
 
Abstract: 
Fungal skin disorders, caused by dermatophytes, yeasts, and molds, represent a significant global health concern, affecting millions of people worldwide. These infections often lead to symptoms such as itching, redness, and scaling, and in some cases, can result in chronic conditions if left untreated. Conventional antifungal treatments, while effective, often come with adverse effects, drug resistance, and high treatment costs. As a result, there is a growing interest in exploring alternative, natural remedies. Delonix regia (Royal Poinciana), a tropical plant known for its antimicrobial, anti-inflammatory, and antioxidant properties, has garnered attention as a potential natural alternative for treating these disorders. This study aims to aggregate the existing data on fungal skin infections and evaluate the therapeutic potential of Delonix regia extract in managing such conditions. Through in vitro and in vivo investigations, the findings suggest that Delonix regia extract demonstrates significant antifungal activity, particularly against dermatophytes, and may serve as an effective complementary treatment in managing fungal skin infections. The plant's multifaceted bioactivity, including its ability to reduce inflammation and oxidative stress, further supports its potential as a valuable adjunct to conventional antifungal therapies.

 
Keywords: 
Delonix regia; Fungal skin disorders; Antifungal; Dermatophytes; Antimicrobial; Plant-based therapy
 
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