Folic acid and its implications in genetic pathology

Cristina-Crenguța Albu 1, *, Dinu-Florin Albu 2, Emily-Alice Russu 1, * and Ştefan-Dimitrie Albu 1

1 University of Medicine and Pharmacy “Carol Davila”, 37 Dionisie Lupu Street, 1st District, 020021,Bucharest, Romania.
2 “Panait Sîrbu” Hospital, 5 Giuleşti Street, 6th District, 060251, Bucharest, Romania.
 
Review Article
World Journal of Advanced Research and Reviews, 2022, 16(01), 742–748
Article DOI: 10.30574/wjarr.2022.16.1.1097
 
Publication history: 
Received on 21 September 2022; revised on 25 October 2022; accepted on 27 October 2022
 
Abstract: 
Vitamins are essential for the proper functioning of the body, and Folic Acid, also known as Vitamin B9, has many benefits for the body. Folic Acid contributes to the normal development of the fetus, preventing the risk of fetal birth defects, mainly represented by neural tube defects and orofacial clefts. At the same time, Folic Acid deficiency can cause serious health problems. That is why it is necessary to know the roles of Folic Acid in the body, the symptoms of Folic Acid deficiency, but also what foods are rich in Folic Acid and how to supplement the body's need for Folic Acid.
 
Keywords: 
Folic Acid; MTHFR C677T gene mutation; Pregnancy; Down Syndrome; Neural tube
 
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