Fertility treatments and breast cancer risk: A case control-retrospective study
1 University of West Attica (UniWA), Athens, Greece.
2 Breast Department, “Alexandra” General Hospital, Athens, Greece.
3 Department of Obstetrics and Gynecology, Democritus University of Thrace, Greece.
4 Breast Department of REA Hospital, Athens, Greece.
5 Medical School, University of Montpellier-Nimes, France.
Research Article
World Journal of Advanced Research and Reviews, 2023, 19(01), 1446–1451
Article DOI: 10.30574/wjarr.2023.19.1.1503
Publication history:
Received on 16 June 2023; revised on 25 July 2023; accepted on 27 July 2023
Abstract:
Objective: To investigate a possible association between fertility treatments and breast cancer (BC) risk in Greek women.
Material-Methods: A series of 391 women who visited two breast clinics in Greece were studied in our case-control retrospective study. The case group comprised 238 women with BC, while the control group had 153 women without BC. All participants were examined clinically and also with breast ultrasound, while those aged over 40 years underwent digital bilateral mammography. All women answered a questionnaire about whether they had received fertility treatment.
Results: Using the Chi-square test, there appears to be no significant statistical association between fertility treatments and BC (p=0.178).
Conclusion: This study did not find a significant association between fertility treatments and BC risk. Further studies with a larger number of patients are mandatory in order to confirm this result. Women considering fertility treatments such as IVF should be informed that it does not appear to increase BC risk.
Keywords:
Breast cancer; Infertility; Fertility treatments; Assisted Reproductive Technology (ART); In Vitro Fertilization (IVF); Breast cancer risk factors.
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0