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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in March 2026 (Volume 29, Issue 3) Submit manuscript

Fertility treatments and breast cancer risk: A case control-retrospective study

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  • Fertility treatments and breast cancer risk: A case control-retrospective study

Anastasia Bothou 1, 2, 3, *, Georgios Iatrakis 1, Stefanos Zervoudis 1, 4, 5, Chrysoula Taskou 1, Georgios Tsatsaris 3 and Panagiotis Tsikouras 3

1 University of West Attica (UniWA), Athens, Greece.
2 Breast Department, “Alexandra” General Hospital, Athens, Greece.
3 Department of Obstetrics and Gynecology, Democritus University of Thrace, Greece.
4 Breast Department of REA Hospital, Athens, Greece.
5 Medical School, University of Montpellier-Nimes, France.
 
Research Article
World Journal of Advanced Research and Reviews, 2023, 19(01), 1446-1451
Article DOI: 10.30574/wjarr.2023.19.1.1503
DOI url: https://doi.org/10.30574/wjarr.2023.19.1.1503
 
Received on 16 June 2023; revised on 25 July 2023; accepted on 27 July 2023
 
Objective: To investigate a possible association between fertility treatments and breast cancer (BC) risk in Greek women.
Material-Methods: A series of 391 women who visited two breast clinics in Greece were studied in our case-control retrospective study. The case group comprised 238 women with BC, while the control group had 153 women without BC. All participants were examined clinically and also with breast ultrasound, while those aged over 40 years underwent digital bilateral mammography. All women answered a questionnaire about whether they had received fertility treatment.
Results: Using the Chi-square test, there appears to be no significant statistical association between fertility treatments and BC (p=0.178).
Conclusion: This study did not find a significant association between fertility treatments and BC risk. Further studies with a larger number of patients are mandatory in order to confirm this result. Women considering fertility treatments such as IVF should be informed that it does not appear to increase BC risk.
 
Breast cancer; Infertility; Fertility treatments; Assisted Reproductive Technology (ART); In Vitro Fertilization (IVF); Breast cancer risk factors.
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2023-1503.pdf

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Anastasia Bothou, Georgios Iatrakis, Stefanos Zervoudis, Chrysoula Taskou, Georgios Tsatsaris and Panagiotis Tsikouras. Fertility treatments and breast cancer risk: A case control-retrospective study. World Journal of Advanced Research and Reviews, 2023, 19(1), 1446-1451. Article DOI: https://doi.org/10.30574/wjarr.2023.19.1.1503

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