Fast dissolving tablets: Opportunity in herbal drug delivery system
1 Assistant Professor, Goel Institute of Pharmacy & Sciences, Lucknow-226028, India.
2 Professor, Institute of Pharmacy, Shri Ramswaroop Memorial University, Lucknow Devaroad, Barabanki 225003, India.
3 Professor, Ved Institute of Pharmacy, Barabanki 225409, India.
Review Article
World Journal of Advanced Research and Reviews, 2024, 21(01), 102–113
Publication history:
Received on 19 November 2023; revised on 27 December 2023; accepted on 30 December 2023
Abstract:
The polyherbal preparation's pharmacological and phytochemical properties have been used all over the world. Single or multiple herbs (polyherbal) are utilized for treatment in Ayurveda. The Sarangdhar Samhita, a work of Ayurvedic literature, emphasized the idea of polyherbalism as a means of enhancing therapeutic efficacy. Individual plants' active phytochemical components are insufficient to produce the desired therapeutic effects. The medicinal effects and toxicity are improved when different herbs are combined in a specific ratio.
Comforts of drug administration and patient compliance are given significant weight when designing dose forms. New and developing technology can be used to produce durable, adaptable tablets with exceptional flavor masking and controlled release. Orally disintegrating tablets (ODTs) are solid dosage forms that disintegrate in the mouth in less than 60 s, and are thus swallowed without the need for water. Rapid disintegration of tablet cause quick dissolution thus rapid onset of action. Polyherbal Fast dissolving Tablets disintegrates in mouth quickly and produces fast onset of action without use of water makes it suitable for special population like pediatrics, geriatrics, psychotic, dysphasic, bedridden patient and frequent traveller patient.
The current review article explains the features of active ingredients and excipient used in the formulation of ODTs, discusses multiple ODT formulation and preparation techniques with their merits and demerits, and also, offers remedies for problems associated with ODTs. Moreover, quality control steps and required considerations are presented.
Keywords:
FDT; Techniques; Super-disintegrants; Evaluation parameters
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